Agrochemicals: Importance, Types and Security
Instituto de Pesquisa Ambiental da Amazônia (IPAM) states that agrochemicals, also known as pesticides, are products intended to control organisms considered pests, which can be harmful to human health and to beings involved in livestock farming, such as cattle or crops. These pesticides can be classified as chemical, physical or biological. Classification of Agricultural Pesticides […]
The Search for Active Molecules in the Pharmaceutical Industry
The search for active molecules is the objective of several pharmaceutical companies around the world. Many of these companies focus their research on plant extracts due to the immense diversity of chemical structures that these extracts offer. History of Drug Discoveries In the past, researchers searched for drugs at random and often, with a little […]
The importance of Cytochrome P450
Cytochrome P450 enzymes are a superfamily of enzymes with similar and, at the same time, structurally distinct functions. These proteins are of utmost pharmacological importance, as they facilitate and increase the excretion of various medications, in addition to being able to inhibit the pharmacological activity of medications in the body. The mechanism involved is complex, […]
COVID-19: Drug Discovery and Repurposing
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, prompted researchers from government agencies and the private sector to look for potential medicines to reduce or eliminate the symptoms of the disease. To accelerate the discovery of an effective drug, both the drug repurposing strategy and the identification of new SARS-CoV-2 proteins were widely used. Computational […]